Getting started

Currently, there are two versions: BrainTrawler Mouse and BrainTrawler Human .

When starting BrainTrawler, the first page will look like this:

On top, you see several tabs. Each tab represents a workflow, see Workflows for a description of the individual tabs.

The workflows you can do with BrainTrawler are:

LITE: This workflow serves as a starting point for dataset exploration: Here, dataset coverage per dataset (e.g. brain region, celltype, phenotype,…) is visualized as a heatmap.

Browse Database: This workflow represents the starting point for all other workflows. The user can browse the data collections and add it to the workspace list.

Network Query: Here, the user can execute target/source queries to explore local brain network connectivity visualized in an anatomical context (2D/3D rendering, bar charts).

Network Analysis: Connectivity can be analyzed and compared as region-level networks on different anatomical scales.

Gene Expression Query: In this workflow, gene expression queries can be performed to see which genes are specific for certain brain regions.

Gene Expression Analysis: Here, one can compare the gene expression for different brain regions or parts of a network.

The list of the public Brain Transcriptomic And Connectivity Data (BrainTACO), you can investigate with BrainTrawler, can be found Data in BrainTrawler .

Some more detailed description of principles and single elements of BrainTrawler are described in Basic Principles and Common UI Elements.

Of interest could also be our video about The Exploration of Heterogeneous Spatial Big Brain Data .